Brain Function and Psychological Changes Related to Cell Therapy for Autoimmune Hemolytic Anemia

Cell therapy is an innovative treatment with significant efficacy in hematologic and certain autoimmune diseases. Although it offers potential benefits for autoimmune hemolytic anemia (AIHA), it may result in cognitive and other potential impairments, which can adversely affect patients' cognition and behavior. Brain function and psychological assessment are essential for the early detection of potential impairments, allowing timely interventions to prevent complications and ensure patient safety. This study aims to comprehensively evaluate the physical and psychological impacts of cell therapy on AIHA patients to develop safer and more effective treatment strategies that enhance their quality of life.

NCT Number	NCT06921980
Lead Sponsor	Institute of Hematology & Blood Diseases Hospital, China Collaborators: Tianjin University
Conditions	CAR T-cell Therapy, Autoimmune Hemolytic Anemia, Brain Function, Psychological Well-Being
Enrollment	20 participants
Start Date	2025-02-25
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-08-05