NCT06921811

Bioavailability From Chickpea Meals in Ileostomists?

StatusCompleted

PhaseNot applicable

SponsorUniversity of Ulster

Primary completionJul 15, 2025

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Record History

All 2 versions: 2 with changes below. See every version on ClinicalTrials.gov ↗

Notable Nov 10, 2026 Eligibility criteria expanded, about 12 words Show 5 more changesShow less
- Trial status changed: Enrolling by Invitation → Completed
- Final enrollment: 13 participants (planned 28)
- Primary completion date changed from estimate of Mar 31, 2026 to Jul 15, 2025
- Start date changed from estimate of Apr 1, 2025 to Mar 19, 2025
- Secondary endpoints: details revised at 8 of 14 entries
Apr 3, 2025 Study First Submitted

Notable: the plan changed

Endpoints

Primary

Ileal fluid energy content

Timeframe: Change over 8 hours comparison between treatments

Secondary (14)

Ileal fluid macronutrient content

Ileal fluid alkylresorcinol content

Ileal fluid carotenoid content

Circulating glucose concentration

Urinary phenolic content

Show 9 moreShow less

Circulating insulin, levels

Circulating essential amino acid levels

Circulating triglyceride levels

Circulating levels of GLP-1

Circulating levels of GIP

Circulating levels of ghrelin

Circulating levels of CKK

Circulating levels of leptin

Circulating levels of bioactive peptides

Arms and interventions

INTACT mealExperimental

BROKEN mealExperimental

Other: Intact chickpeas, Broken chickpeas

Sites

1 site in 1 country

Human Intervention Studies Unit, Ulster UniversityColeraine, N.Ireland, United Kingdom

About this trial

The matrix of a food can significantly affect how well humans can absorb and use nutrients. Plants like fruits, vegetables, nuts, grains, and legumes have cell walls that form a network around their cells. These cell walls are a barrier for the digestive system to break down completely, which can make it harder to digest the food and get energy from it. This study will explore how the integrity of plant cell walls affects how well humans can absorb macronutrients (protein, fat and carbohydrates) and beneficial compounds e.g. phytochemicals. The study will compare two chickpea meals that have similar nutrients and energy content but differ in the amount of intact plant cell walls e.g. chickpea salad meal (INTACT diet) and chickpea burger meal (BROKEN diet).

Trial details

Enrollment: 13 participants (actual)
Started: Mar 19, 2025
Study completion: Jul 15, 2025
Eligibility: 18 to 60, all sexes, healthy volunteers accepted
Design: Interventional, randomized, single blind, other
Oversight: No data monitoring committee
Conditions: Nutrition, Absorption, Polyphenolic Compounds and Metabolism, Polyphenols Absorption Profile, Energy Availability
Collaborators: Wageningen University and Research
Official title: Bioavailability of Macronutrients and Bioactive Compounds From Chickpea Meals: an Ileostomy Study.
First posted: Apr 10, 2025
Registry updated: Nov 12, 2026
Last verified: Nov 2026

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