Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients

This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendations for the treatment of overactive bladder (OAB). A portion of urine samples, which are routinely collected for biochemical and culture examinations as part of the diagnostic process, will be sent for examination of the characteristics of the urinary microbiome and metabolome (UMM) before and after treatment.

NCT Number	NCT06921746
Lead Sponsor	University Hospital Ostrava Collaborators: University Hospital Bulovka, Thomayer University Hospital, Institute of Microbiology of the Czech Academy of Sciences
Conditions	Overactive Bladder
Enrollment	80 participants
Start Date	2025-05-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-05-04