Clinical Trial

Effect of Ephedrine vs. Norepinephrine on Prevention of Fetal Acidosis During Cesarean Section Under Spinal Anesthesia

Study acronym: NEO-FET
Completed Phase 4
View on ClinicalTrials.gov →
Summary
This study compares the effects of two medications, ephedrine and norepinephrine, on the baby (fetus) when used to treat low blood pressure (hypotension) during cesarean section under spinal anesthesia. Hypotension is a common side effect during spinal anesthesia, and it can affect the blood flow to the baby. Both medications are commonly used to manage this condition. The goal of the study is to determine which medication is more effective and safer for the baby, by measuring the pH level in the umbilical artery after birth. The study will also examine maternal blood pressure, heart rate, and the baby's Apgar scores.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-04-08; most recent amendment 2025-12-26.
Status change: Recruiting → Completed 2025-12-26
Status change: Not Yet Recruiting → Recruiting 2025-11-17
Trial Details
NCT Number NCT06921473
Lead Sponsor mehmet özkılıç
Conditions Cesarean Delivery Affecting Newborn, Acidosis, Maternal Hypotension, Spinal Aneshtesia
Enrollment 102 participants
Start Date 2025-09-01
Primary Completion 2025-12-12 (estimated)
Study Completion 2025-12-15 (estimated)
Updated on ClinicalTrials.gov 2025-12-29