HLA Antibodies in Systemic Lupus Erythematosus

Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.

NCT Number	NCT06921239
Lead Sponsor	Centre Hospitalier Universitaire, Amiens
Conditions	HLA Antibodies, Systemic Lupus Erythematosus
Enrollment	30 participants
Start Date	2025-02-10
Primary Completion	2026-11 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-01-16