Clinical Trial

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Immunogenicity of APG777 in Adults With Asthma

Active, Not Recruiting Phase 1
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Summary
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, PK, and immunogenicity of APG777 in adult participants with mild-to-moderate asthma. The duration of the study will be approximately 52 weeks (364 days) for each participant and will consist of a Screening Period, Treatment Period, and Follow-up Period.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-04-08; most recent amendment 2026-02-12.
Status change: Recruiting → Active, Not Recruiting 2025-09-08
Trial Details
NCT Number NCT06920901
Lead Sponsor Apogee Therapeutics, Inc.
Conditions Asthma
Enrollment 31 participants
Start Date 2025-03-27
Primary Completion 2026-09 (estimated)
Study Completion 2027-03 (estimated)
Updated on ClinicalTrials.gov 2026-02-17