Effect of a Protein-Creatine-Omega3-Vitamin D Supplement on Glycemic Variability in Mexican Patients With Type 2 Diabetes

This study aims to evaluate the effect of a daily nutritional supplement containing whey protein, creatine, omega-3 fatty acids, and vitamin D on blood sugar fluctuations in adults with recently diagnosed type 2 diabetes. Forty participants will be enrolled in a 12-week, double-blind, randomized clinical trial. Half of the participants will receive the supplement, while the other half will receive a placebo. Blood sugar levels will be monitored using continuous glucose monitoring (CGM) devices placed at five different time points during and after the intervention. The study will also measure changes in HbA1c, body composition, metabolic biomarkers, and gut microbiota. Participants will receive medical follow-up and support for six months after the study. The goal is to explore whether this supplement can help stabilize glucose levels and support early management of diabetes.

NCT Number	NCT06920667
Lead Sponsor	Héctor Iván Saldívar Cerón Collaborators: University of Illinois at Chicago
Conditions	Type 2 Diabetes Mellitus
Enrollment	40 participants
Start Date	2025-06-01
Primary Completion	2026-05-01 (estimated)
Study Completion	2026-10-25 (estimated)
Updated on ClinicalTrials.gov	2025-04-13