Clinical Trial

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Completed Phase 1
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression. The main question it aims to answer is: What is the usability, feasibility, and acceptability of Therabot-CALM in persons with Cannabis Use Disorder and Anxiety and/or Depression? Participants will * Take a screening questionnaire * Participate in two virtual 1-hour interviews to provide feedback on app design and suggest features. * Engage with Therabot-CALM in a 4-week clinical trial and provide feedback on their app experience in a third virtual interview
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-04-02; most recent amendment 2026-07-02.
Status change: Recruiting → Completed 2026-07-02
Status change: Not Yet Recruiting → Recruiting 2025-04-17
Trial Details
NCT Number NCT06920238
Lead Sponsor Trustees of Dartmouth College
Collaborators: National Institute on Drug Abuse (NIDA)
Conditions Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
Enrollment 15 participants
Start Date 2025-04-13
Primary Completion 2026-04-28 (estimated)
Study Completion 2026-04-28 (estimated)
Updated on ClinicalTrials.gov 2026-07-06