HOTSPOT Study: Implement and Evaluate the PrEP (Pre-exposure Prophylaxis) Implementation Strategy

The goal of this study is to measure the implementation and effectiveness of a multicomponent strategy for PrEP for people who are incarcerated at the Dallas County Jail. Specifically, based on a patients risk score on an electronic medical record HIV prediction model, referrals from providers and/or patient self-referrals, a PrEP patient navigator will meet with individuals at the jail to discuss HIV risk, offer HIV/STI testing if not yet completed and offer education around PrEP with referrals to community-based PrEP providers.

NCT Number	NCT06919419
Lead Sponsor	University of Texas Southwestern Medical Center Collaborators: National Institute of Mental Health (NIMH)
Conditions	PrEP, HIV, Incarceration
Enrollment	3,600 participants
Start Date	2025-03-01
Primary Completion	2027-02-01 (estimated)
Study Completion	2027-08-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-10