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Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease

StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated January 29, 2026 (before its estimated March 15, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study title expanded, about 8 wordsv4 See this version in full on ClinicalTrials.gov ↗
  2. Lead sponsor: [Redacted] to University of Illinois at Chicago Trial status: Withheld to Recruiting · Primary completion date: Mar 15, 2026 · Completion date: Jun 15, 2026 · 3 morev3 Show 6 more changesShow less
    • Trial status: Withheld to Recruiting
    • Primary completion date: Mar 15, 2026
    • Completion date: Jun 15, 2026
    • Start date: Aug 1, 2025
    • Collaborators expanded, about 9 words
    • Study title shortened, about 10 words

    See this version in full on ClinicalTrials.gov ↗

  3. Re-verified, no change to tracked fieldsv2
  4. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
In this phase II randomized double-masked clinical trials, subjects with non-resolving corneal epithelial disease/defect (i.e., refractory to standard treatments for at least two weeks) will receive 8 weeks treatment of topical mesenchymal stem cell secretome or vehicle, with continued follow-up for up to Day 70.
Trial Details
NCT Number NCT06919081
Lead Sponsor University of Illinois at Chicago
Collaborators: National Eye Institute (NEI), National Institutes of Health (NIH)
Conditions Persistent Corneal Epithelial Defect, Corneal Epithelial Disorders
Enrollment 24 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov