Clinical Trial

Latency Antibiotics for Previable Rupture Of Membranes Trial

Study acronym: LAPROM

Withdrawn Phase 4

View on ClinicalTrials.gov →

Why the trial stopped

PI has decided to end study due to changes in Texas law and no participants were enrolled

Summary

The purpose of this study is to see if the use of prophylactic antibiotics in the expectant management of PPROM less than 22 weeks significantly reduce the rate of delivery within 7 days and to see if the use of prophylactic antibiotics in the expectant management of PPROM between 20 and 22 weeks decrease composite neonatal morbidity.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-03-31.

Status change: Not Yet Recruiting → Withdrawn 2026-04-29

Trial Details

NCT Number	NCT06917157
Lead Sponsor	The University of Texas Health Science Center, Houston
Conditions	Preterm Prelabor Rupture of Membranes (PPROM)
Start Date	2025-05-01
Primary Completion	2026-05-31 (estimated)
Study Completion	2027-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-06