Clinical Trial

Renal Perfusion and the Development of AKI Following Traumatic Injury

Study acronym: PERTAKI
Recruiting
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Record status
This record was last updated April 8, 2025 (before its estimated January 2026 completion). Its status may not reflect the trial's current state.
Summary
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.
Trial Details
NCT Number NCT06917053
Lead Sponsor King's College Hospital NHS Trust
Conditions Traumatic Haemorrhagic Shock, AKI (Acute Kidney Injury) Due to Trauma, AKI - Acute Kidney Injury
Enrollment 20 participants
Start Date 2024-04-13
Primary Completion 2026-01 (estimated)
Study Completion 2026-07 (estimated)
Updated on ClinicalTrials.gov 2025-04-08