Clinical Trial

Food Challenge at Home or in Medical Practice - the FoodCHOMP Study

Study acronym: CHOMP
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated April 17, 2025 (before its estimated July 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This is a pilot, multi-centre, randomised clinical trial evaluating the safety and feasibility of a home-based oral food challenge in adults with low-risk food allergy labels. Eligible participants are aged 18 years or older and have a self-reported food allergy with negative skin prick testing to the implicated food. Participants will be randomised to either a home-based or standard in-clinic food challenge. The primary aim is to determine the safety of home challenges, measured by the rate of immune-mediated adverse events. Secondary aims include feasibility of recruitment and delivery, protocol adherence, quality of life, and food reintroduction outcomes.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-04-01; most recent amendment 2025-04-15.
Status change: Not Yet Recruiting → Recruiting 2025-04-15
Trial Details
NCT Number NCT06916819
Lead Sponsor Austin Health
Collaborators: Royal Melbourne Hospital, Australia
Conditions Food Allergies
Enrollment 120 participants
Start Date 2025-04-16
Primary Completion 2026-07-01 (estimated)
Study Completion 2026-12-01 (estimated)
Updated on ClinicalTrials.gov 2025-04-17