MR Elastography in Intracranial Lesions: Feasibility & Accuracy

Brain tumors, despite their relatively low incidence among cancers, are associated with high morbidity and mortality due to the brain's complexity. Biopsy, the gold standard for tumor grading, is limited by invasiveness, costs, and sampling issues. Conventional MR imaging lacks sensitivity to differentiating tumor grades, while magnetic resonance elastography (MRE) offers non-invasive assessment potential. This retrospective study reviewed MRE data from 626 brain tumor patients (May 2017-September 2025) to evaluate MRE's diagnostic performance, success rate in tumor grading, and clinical reliability, aiming to advance its role in non-invasive brain tumor assessment.

NCT Number	NCT06916715
Lead Sponsor	Shengjing Hospital
Conditions	Brain Neoplasms
Enrollment	626 participants
Start Date	2017-05-09
Primary Completion	2026-09-25 (estimated)
Study Completion	2026-12-09 (estimated)
Updated on ClinicalTrials.gov	2026-04-30