Clinical Trial

Modulation of the Inflammatory Response in Bariatric Surgery

Study acronym: MRICBx3
Recruiting
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Record status
This record was last updated April 8, 2025 (before its estimated December 2, 2025 completion). Its status may not reflect the trial's current state.
Summary
This study will evaluate how different anesthesia techniques affect inflammation after bariatric surgery. Patients will be randomly assigned to receive one of three approaches: opioid-free anesthesia, intravenous anesthesia with opioids, or inhalational anesthesia with opioids. The study will measure blood levels of inflammation-related substances (such as IL-6, CRP, cortisol, ESR , WBC and lactate) at several time points before and after surgery. Heart rate variability will also be monitored as an indicator of the body's stress response. The results may help identify anesthesia strategies that reduce inflammation and improve recovery in patients undergoing bariatric surgery.
Trial Details
NCT Number NCT06915558
Lead Sponsor Hospital HM Nou Delfos
Conditions Obesity, Bariatric Surgery Candidate, Inflammation, Postoperative Pain, Opioid-Free Anesthesia, Heart Rate Variability
Enrollment 90 participants
Start Date 2024-12-02
Primary Completion 2025-12-02 (estimated)
Study Completion 2025-12-02 (estimated)
Updated on ClinicalTrials.gov 2025-04-08