Lipid Infusions to Optimize Nutrition Trial

The purpose of this study is to identify survival free of bronchopulmonary dysplasia (BPD), fatty acid profiles, and early biochemical measures for oxidative stress comparing mixed oil lipid emulsion (MOLE) vs soybean oil-based lipid emulsion (SOLE) and to establish whether MOLE or SOLE is more effective in minimizing pulmonary outcomes, neonatal morbidities, long-term morbidity and mortality, and improving discharge growth and Bayley Scales of Infant Development Fourth Edition (BSID-IV) neurodevelopmental assessment at two years

NCT Number	NCT06915441
Lead Sponsor	The University of Texas Health Science Center, Houston
Conditions	Bronchopulmonary Dysplasia, Neurodevelopmental Impairment
Enrollment	230 participants
Start Date	2026-04-29
Primary Completion	2028-07-30 (estimated)
Study Completion	2030-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-08-06