Clinical Trial

A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle

Study acronym: MASCOT
Recruiting Phase 3
View on ClinicalTrials.gov →
Summary
The objective of this study is to demonstrate the superiority of MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimulation in the treatment of patients aged 17 to 65 years with symptomatic articular chondral or osteochondral defects of the talus.
Protocol Amendment History 1 change
notable Trial sites expanded: 4 -> 7 locations 2026-07-24
Trial Details
NCT Number NCT06915233
Lead Sponsor Vericel Corporation
Conditions Chondral Defect, Articular Cartilage Defect
Enrollment 309 participants
Start Date 2026-05-28
Primary Completion 2030-07 (estimated)
Study Completion 2030-07 (estimated)
Updated on ClinicalTrials.gov 2026-07-23