Oxygenation Procedure for Obese Patients During Intubation in the Operating Room

Obesity is a risk factor for difficult intubation, with an incidence of up to 15.5%, and difficult mask ventilation. Obesity also reduces the functional residual capacity (FRC) of the lungs, the main reservoir of oxygen during apnoea. Complications associated with induction and intubation in the operating room are more frequent in obese patients. Preoxygenation is a cornerstone in the management of patients at risk of desaturation during induction. The study aims to compare two oxygenation strategies , in obese patients. Oxygenation using a combination of NIV (Non Invasive Ventilation) and HFNO (High Flow Nasal Oxygen) compared with NIV alone in the operating room for induction of general anaesthesia with orotracheal intubation.

NCT Number	NCT06914401
Lead Sponsor	Clinique Pasteur
Conditions	Anesthesia Induction
Enrollment	124 participants
Start Date	2025-06-19
Primary Completion	2026-05-04 (estimated)
Study Completion	2026-05-04 (estimated)
Updated on ClinicalTrials.gov	2026-06-15