Assessing Patient Comfort, Anxiety, and Satisfaction During CR Comparing Conventional Drops With ROC

This study aims to compare the efficacy of conventional cycloplegic agents, such as cyclopentolate, with rapid-onset cycloplegics, like a combination of tropicamide and phenylephrine, in reducing patient anxiety and discomfort during cycloplegic refraction. Cycloplegic refraction is an essential procedure for diagnosing refractive errors, particularly in children, by temporarily paralyzing the ciliary muscle to inhibit accommodation. While cyclopentolate has a relatively quick onset, tropicamide is preferred due to its faster onset and shorter duration. Despite its advantages, concerns about patient discomfort and anxiety during the procedure remain, especially in pediatric populations.

NCT Number	NCT06914063
Lead Sponsor	Superior University
Conditions	Cycloplegic Paralysis of Accommodation
Enrollment	74 participants
Start Date	2025-03-20
Primary Completion	2025-06-20 (estimated)
Study Completion	2026-02-20 (estimated)
Updated on ClinicalTrials.gov	2025-04-06