A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users

This clinical trial evaluates a smartphone application (app) called Acceptance and Commitment Therapy (ACT) on Vaping for helping young adults quit using electronic cigarettes (e-cigarettes). E-cigarettes pose numerous risks, particularly to youth and young adults. Addressing the high prevalence of e-cigarette use by young adults requires effective and accessible treatments to support current users to quit. Research shows this group prefers and benefits from newer methods of treatment delivery such as digital interventions. ACT on Vaping is a digital therapeutic intended to deliver behavioral therapy to young adults who vape to motivate and support abstinence from all nicotine and tobacco products. The app contains sessions that promote awareness of cues that trigger tobacco use and teach skills for responding to these triggers in a way that is tailored for the participant's readiness to quit. Receiving access to the ACT on Vaping app may be effective in helping young adults quit vaping.

NCT Number	NCT06909500
Lead Sponsor	Fred Hutchinson Cancer Center Collaborators: National Institute on Drug Abuse (NIDA)
Conditions	Nicotine Dependence, Tobacco-Related Carcinoma
Enrollment	1,178 participants
Start Date	2026-08-15
Primary Completion	2027-11-15 (estimated)
Study Completion	2027-11-15 (estimated)
Updated on ClinicalTrials.gov	2026-07-23