Clinical Trial

Impact of Perioperative Organ Resuscitation of Brain-dead Deceased Organ Donor on Kidney Graft Function in the Recipient

Study acronym: OPTI-PMO 2
Recruiting
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Record status
This record was last updated April 2, 2025 (before its estimated December 10, 2025 completion). Its status may not reflect the trial's current state.
Summary
Brain-dead patients are the primary source of grafts for those awaiting organ transplantation. Recommendations exist for the management of these potential donors, based on the concept of organ resuscitation, according to which targeted resuscitation would improve graft quality and quantity. Graft performance thus depends on fixed factors (donor/recipient age, medical history, etc.) but also potentially modifiable factors. Through this study, the investigators aim to identify potentially modifiable factors in our donor care (in intensive care and the operating room) that may influence graft function in the recipient. For simplicity, the investigators will focus on kidney grafts. The aim is to improve the effectiveness of the transplant and reduce waiting times.
Trial Details
NCT Number NCT06907758
Lead Sponsor University Hospital, Strasbourg, France
Conditions Kidney Graft
Enrollment 50 participants
Start Date 2024-04-10
Primary Completion 2025-12-10 (estimated)
Study Completion 2025-12-10 (estimated)
Updated on ClinicalTrials.gov 2025-04-02