Blood Flow Restriction in Older Adults

Introduction. From the age of 80 onwards, more than 50% of people suffer from sarcopenia. The loss of muscle strength leads to a loss of muscle power, impairing functionality and preventing the correct performance of activities of daily living. Objective. To analyse the efficacy of blood flow restriction in older adult patients by evaluating changes in the variables muscle power and strength, physical condition and functionality of the lower limbs. Material and method. Randomised single-blind clinical study. Thirty-six older adults will be recruited and randomised to the experimental and control groups. The intervention will have a duration of 4 weeks, with 2 weekly sessions. The intervention will consist of an intervention by performing 3 quadriceps strength exercises, with a 40% restriction. The primary variable of the study will be muscle power (Sit To Stand 5 times) and the secondary variables will be muscle strength (dynamometry), physical condition (Timed Up and Go) and functionality and autonomy (Barthel index)

NCT Number	NCT06906523
Lead Sponsor	Universidad Católica San Antonio de Murcia
Conditions	Older Patients
Enrollment	18 participants
Start Date	2025-03-12
Primary Completion	2025-04-13 (estimated)
Study Completion	2025-04-15 (estimated)
Updated on ClinicalTrials.gov	2025-04-04