Multimodal Cardiovascular and Hepatic Population Imaging

Medical imaging is increasingly important for understanding diseases, detecting them early, and personalizing treatments. New imaging techniques, which can measure processes in the body without surgery, are opening the door to a more precise approach to medicine. Instead of relying on general probabilities, this technology allows us to analyze specific factors in a person's health, leading to better predictions and targeted treatments. One key challenge in medicine today is reducing "residual individual risk"-the remaining health risks that current treatments don't fully address. This involves understanding how factors like age, sex, genetics, and environment affect our health, particularly when it comes to conditions like heart and liver disease. By using imaging to distinguish between normal aging and disease, we can better assess individual health risks. The current project will create a large collection of medical images linked with health data from a broad population across France. Using advanced, non-invasive techniques such as MRI and ultrasound, researchers will analyze the heart, blood vessels, and liver in detail, considering factors like gender and health risk profiles. This will help improve our understanding of these diseases, which are often silent and not well understood, providing direct benefits to the participants. Ultimately, the goal is to optimize imaging technologies for large-scale studies, which will help enhance early detection and prevention for everyone.

NCT Number	NCT06906042
Lead Sponsor	Institut National de la Santé Et de la Recherche Médicale, France
Conditions	Healthy Volunteers, Imaging Evaluation
Enrollment	2,400 participants
Start Date	2025-09-15
Primary Completion	2030-03-14 (estimated)
Study Completion	2033-03-14 (estimated)
Updated on ClinicalTrials.gov	2026-01-23