Novel Cavity Marking Technique in Breast Cancer Patients Undergoing Breast Conservation Surgery With Oncoplastic Reconstruction for the Delivery of Adjuvant Radiotherapy and Accuracy of Recommended Re-excisions

This study will investigate a novel approach to marking surgical cavity margins following tumor resection, to allow for more accurate radiotherapy following oncoplastic surgery. Our proposed cavity marking schema will allow radiation oncology to identify the cavity margins more accurately on CT simulation for radiation planning and delivery. This cavity marking schema also provides more accurate margin identification in patients recommended for re-excision of close or positive margins.

NCT Number	NCT06903468
Lead Sponsor	University of Florida
Conditions	Ductal Carcinoma in Situ, Breast Cancer
Enrollment	50 participants
Start Date	2025-10-27
Primary Completion	2027-11 (estimated)
Study Completion	2029-11 (estimated)
Updated on ClinicalTrials.gov	2025-12-15