Clinical Trial

Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia

Study acronym: ESTER

Not Yet Recruiting

Summary

This prospective observational cohort study aims to compare the clinical and procedural outcomes of Endoscopic Submucosal Dissection (ESD) and Transanal Minimally Invasive Surgery (TAMIS) for the treatment of early-stage rectal neoplasia. The study will evaluate recurrence rates, en bloc resection rates, R0 resection rates, procedure time, complication rates, and length of hospital stay over a 1-year follow-up period. Data will be collected from patients treated at multiple centers with expertise in ESD and TAMIS.

Protocol Amendment History 2 amendments

This ClinicalTrials.gov record has been amended 2 times since 2025-03-27; most recent amendment 2025-06-18.

Trial Details

NCT Number	NCT06902701
Lead Sponsor	Turkish Society of Colon and Rectal Surgery
Conditions	Rectal Neoplasms
Enrollment	156 participants
Start Date	2025-07-01
Primary Completion	2027-06-01 (estimated)
Study Completion	2028-07-01 (estimated)
Updated on ClinicalTrials.gov	2025-06-24