Brain Network Stimulation for Chronic Low Back Pain.

This study looks at the non-invasive brain stimulation technique in people with chronic low back pain to see: * How effective non-invasive brain stimulation is at improving pain intensity in people with chronic low back pain? * How safe non-invasive brain stimulation is and what side effects there may be? * What study participants think of the study procedures and of the non-invasive brain stimulation as a treatment technique for chronic low back pain. Participants will be assigned to receive either active brain stimulation group or sham stimulation group randomly. Participants will be required to attend a total of twelve treatment sessions (approximately 1-hour each, three sessions per week, for four consecutive weeks). Assessments will be done at baseline (in the week 0), immediately post-completion of the intervention (in the week 5), and at the follow-up of one-month (in the week 8), three-months (in the week 16) and six-months (in the week 28) post-completion of intervention.

NCT Number	NCT06902233
Lead Sponsor	University of Otago Collaborators: Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Conditions	Chronic Low Back Pain (CLBP)
Enrollment	164 participants
Start Date	2025-06-12
Primary Completion	2027-06 (estimated)
Study Completion	2028-01 (estimated)
Updated on ClinicalTrials.gov	2025-07-31