Ventilator Settings and Outcomes in Pediatric Patients on ECMO for Severe Respiratory Failure

This study aims to describe the effects of ECMO initiation on the intensity of ventilation in the first 24 hours after ECMO initiation and to explore associations between changes in ventilation intensity and hospital mortality in critically ill pediatric patients requiring ECMO for respiratory failure, using the 'Extracorporeal Life Support Organization' (ELSO) registry.

NCT Number	NCT06899009
Lead Sponsor	University Medical Center Groningen Collaborators: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions	Critical Illness, Respiratory Failure (Pediatric Patients)
Enrollment	750 participants
Start Date	2024-09-01
Primary Completion	2025-03-01 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-03-27