Clinical Trial

Intracardiac Echocardiography-Guided Catheter Ablation for Premature Ventricular Contractions Originating From the Papillary Muscles

Active, Not Recruiting
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Record status
This record was last updated April 24, 2025 (before its estimated March 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized, prospective, parallel, single-blind, multicenter clinical trial investigates the efficacy and safety of intracardiac echocardiography (ICE)-guided catheter ablation versus pressure-sensing catheter ablation alone in reducing PVC recurrence among patients with confirmed papillary muscle-originating premature ventricular contractions (PVCs). Participants were randomly allocated to either the ICE-guided intervention group or the conventional ablation control group following definitive diagnosis.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-03-22.
Trial Details
NCT Number NCT06898281
Lead Sponsor Shanghai Chest Hospital
Collaborators: The Second People's Hospital of Anhui Province, The First People's Hospital of Hefei, Qilu Hospital of Shandong University, Fujian Medical University Union Hospital, Chinese Academy of Medical Sciences, Fuwai Hospital
Conditions Premature Ventricular Contractions
Enrollment 156 participants
Start Date 2025-03-23
Primary Completion 2026-03-01 (estimated)
Study Completion 2026-03-01 (estimated)
Updated on ClinicalTrials.gov 2025-04-24