Clinical Trial

Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related Biomarkers

Completed Phase 4
View on ClinicalTrials.gov →
Summary
This study aimed to evaluate whether dexmedetomidine has a protective effect on endothelial damage by measuring plasma syndecan1 and heparan sulphate levels in rhinoplasty patients who take propofol+remifentanyl infusion.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-03-26; most recent amendment 2026-01-01.
Status change: Active, Not Recruiting → Completed 2026-01-01
Status change: Not Yet Recruiting → Active, Not Recruiting 2025-08-15
Trial Details
NCT Number NCT06897696
Lead Sponsor Firat University
Conditions Endothelial Damage, Dexmedetomidine, Syndecan 1, Heparan Sulpahate
Enrollment 90 participants
Start Date 2025-04-10
Primary Completion 2025-10-31 (estimated)
Study Completion 2025-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-06