Comparing Unilateral and Bilateral Proximal GONPRF in Migraine Treatment

This study is designed to compare the clinical effectiveness of unilateral and bilateral Greater Occipital Nerve Pulsed Radiofrequency (GON-PRF) treatment at the C2 level in patients with migraine. The procedure will be guided by ultrasound and will focus on evaluating how each technique affects migraine symptoms. The main goal of this study is to assess the impact of both unilateral and bilateral GON-PRF treatments on migraine relief. Additionally, the secondary objectives of this study include evaluating the effects of these treatments on migraine-related disability and comparing any potential side effects or complications that may occur during the treatments. This research will help us understand which technique may be more effective and provide more information on the safety of these treatments.

NCT Number	NCT06894121
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Migraine, Greater Occipital Nerve Pulsed Radiofrequency, Headache Disorders, Ultrasound Guided Nerve Block
Enrollment	217 participants
Start Date	2024-12-18
Primary Completion	2026-04-01 (estimated)
Study Completion	2026-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-05-07