Clinical Trial

Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain

Not Yet Recruiting Early Phase 1
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Record status
This record was last updated March 26, 2025 (before its estimated May 2025 completion). Its status may not reflect the trial's current state.
Summary
The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis (SIP/SAP). The main question it aims to answer: Is there an analgesic effect of extruding an intracanal solution of DXA into the periapical tissues in patients diagnosed with SIP/SAP? Researchers will compare dexamethasone to a placebo to see if the extrusion dexamethasone works in reducing post-endodontic treatment pain.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-03-23.
Trial Details
NCT Number NCT06894069
Lead Sponsor University of Jordan
Conditions Post Operative Pain Control, Endodontic Treatment
Enrollment 80 participants
Start Date 2025-03
Primary Completion 2025-05 (estimated)
Study Completion 2025-05 (estimated)
Updated on ClinicalTrials.gov 2025-03-26