Clinical Trial

Effect of an Intervention Program of Adapted Physical Activity Combined With Compensatory Nutrition in Patients With Constitutional Thinness

Study acronym: ANIMATION
Recruiting
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Record status
This record was last updated October 7, 2025 (before its estimated March 2026 completion). Its status may not reflect the trial's current state.
Summary
Constitutional Thinness (CT) is a form of stable thinness without malnutrition but with resistance to weight gain, affecting approximately 1% of the general population. The clinical consequences are numerous and the pathophysiology remains poorly understood. Currently, conventional management involves a high-calorie and frequent diet, combined with the avoidance of endurance physical activity, although there is no significant evidence of its effectiveness. Our hypothesis is that an adapted physical activity program (APA) combined with compensatory nutrition (CN) could help these patients gain lean mass (muscle mass).
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-03-18; most recent amendment 2025-10-02.
Status change: Not Yet Recruiting → Recruiting 2025-10-02
Trial Details
NCT Number NCT06894043
Lead Sponsor Centre Hospitalier Universitaire de Saint Etienne
Collaborators: Laboratoire Interuniversitaire de Biologie de la Motricité, Target Tape
Conditions Constitutional Thinness
Enrollment 62 participants
Start Date 2025-07-07
Primary Completion 2026-03 (estimated)
Study Completion 2026-06 (estimated)
Updated on ClinicalTrials.gov 2025-10-07