Clinical Trial

Multicenter Prospective Observational Study on Diaphragmatic Function Assessment by Ultrasound in Patients With Acute Respiratory Failure Receiving Non-invasive Mechanical Ventilation or High Flow Nasal Canula

Study acronym: DIAFUSION
Active, Not Recruiting
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Summary
The primary goal of this study is to assess diaphragm function in patients with acute respiratory failure before and during the use of high-flow oxygen and/or non-invasive breathing support. The key question it seeks to answer is: 1\. How do ultrasound measurements of diaphragmatic function vary with different levels of breathing support in patients with acute respiratory failure? Participants with acute respiratory failure will undergo diaphragmatic ultrasound evaluation as part of their standard medical care at various levels of respiratory support.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-03-21.
Status change: Not Yet Recruiting → Active, Not Recruiting 2026-05-14
Trial Details
NCT Number NCT06892912
Lead Sponsor Foro Internacional en Cuidado Crítico
Conditions Respiration Disorders
Enrollment 100 participants
Start Date 2025-08-02
Primary Completion 2026-10-01 (estimated)
Study Completion 2026-10-01 (estimated)
Updated on ClinicalTrials.gov 2026-05-18