ROTEM in Sepsis Trauma Outcome in Intensive Care

This prospective observational study aims to investigate the ability of advanced ROTEM analysis using Principal Component Analysis (PCA) to detect early signs of disseminated intravascular coagulation (DIC) and trauma-induced coagulopathy (TIC) in hospitalized patients with sepsis or trauma. Standard coagulation tests and ROTEM measurements will be collected and analyzed in relation to clinical outcomes.

NCT Number	NCT06891599
Lead Sponsor	Region Stockholm
Conditions	Sepsis - to Reduce Mortality in the Intensive Care Unit, Trauma Coagulopathy
Enrollment	600 participants
Start Date	2024-11-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-03-24