Clinical Trial

Immediate Chemotherapy Following Resection for High-Risk Non-Muscle-Invasive Bladder Cancer

Study acronym: HIGCrecur
Recruiting
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Record status
This record was last updated March 21, 2025 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Residual tumors after transurethral resection of bladder tumors (TURBT) range from 17-70%, and floating tumor cells from traditional segmental resection may lead to recurrence if they re-implant in the bladder wall. Immediate systemic chemotherapy post-surgery aims to eliminate microlesions promptly and minimize recurrence risk, yet its safety and efficacy require further exploration. This prospective, single-arm study delves into evaluating the efficacy and safety of immediate postoperative systemic chemotherapy in patients with suspected high-risk non-muscle-invasive bladder cancer.
Trial Details
NCT Number NCT06889623
Lead Sponsor Changhai Hospital
Conditions NMIBC
Enrollment 72 participants
Start Date 2024-06-01
Primary Completion 2026-06-01 (estimated)
Study Completion 2028-06-01 (estimated)
Updated on ClinicalTrials.gov 2025-03-21