Comparison of Preoperative Frailty Assessment Tools

Frailty is a significant risk factor for postoperative complications and functional decline. Preoperative assessment of frailty is therefore recommended in all older adults. However, despite the availability of many frailty tools, few have been tested in the preoperative setting and there is little comparison of their predictive value in identifying patients at risk. The aim of this study is to investigate which of the following instruments for determining frailty has the highest predictive power with regard to the occurrence of postoperative complications: Risk Analysis Index, Clinical Frailty Scale, the Groningen Frailty Indicator, the Edmonton Frail Scale and the LUCAS-FI. The aim of this research project is to identify a suitable frailty instrument for preoperative risk stratification of older patients during the premedication visit.

NCT Number	NCT06889545
Lead Sponsor	Universitätsklinikum Hamburg-Eppendorf
Conditions	Frailty, Frailty in Older Adults, Frailty/Sarcopenia
Enrollment	584 participants
Start Date	2025-04-15
Primary Completion	2027-11-01 (estimated)
Study Completion	2028-04-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-22