Clinical Trial

Spinal Cord Injury: Impact on Sensory, Motor, Behavioral and Cognitive Functions

Study acronym: SUPRASPINAL
Not Yet Recruiting
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Record status
This record was last updated March 20, 2025 (before its estimated April 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
Spinal cord injury (SCI) causes a variety of sensory-motor deficits and neuropsychological consequences. Magnetic resonance imaging (MRI) reveals a reduction in the volume of the somato-sensory and motor cortices, as well as atrophy in the white matter bundles. In addition, disturbances in cerebral activity are observed in several areas, notably the motor cortex and the prefrontal cortex. The aim of this study is to understand the evolution of brain function after SCI in comparison with a control group of healthy volunteers. We distinguish between patients with incomplete sensorimotor deficits (ASIA B,C,D) and complete sensorimotor deficits (ASIA A). Both patient groups will have a multimodal assessment at 1 week, 3 months and 12 months after SCI with MRI and neuropsychological tests. The group of healthy volunteers will only perform one MRI.
Trial Details
NCT Number NCT06887309
Lead Sponsor University Hospital, Montpellier
Conditions Spinal Cord Injury
Enrollment 30 participants
Start Date 2025-04-15
Primary Completion 2026-04-15 (estimated)
Study Completion 2027-10-01 (estimated)
Updated on ClinicalTrials.gov 2025-03-20