SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation

The study is sponsored by the National Heart, Lung, and Blood Institute, which is part of the National Institutes of Health. The study expects to enroll 400 subjects. The research team will recruit research participants that are finishing or will finish cardiac rehabilitation soon. Participants belong to one or more groups of people who are less often studied in cardiac rehabilitation research, may have less access to a formal cardiac rehabilitation maintenance program, or they may especially benefit from additional support after cardiac rehabilitation ends. The main purposes of this study are to evaluate which treatments work the best after cardiac rehabilitation, which order to deliver the treatments in, and which treatments are as minimally burdensome as possible while still working well. This study will make two comparisons (one comparison between a set of low-intensity interventions and another between a set of higher-intensity interventions) to determine which produces the best behavioral adherence immediately after Phase II (outpatient) cardiac rehabilitation

NCT Number	NCT06886789
Lead Sponsor	The Miriam Hospital Collaborators: National Heart, Lung, and Blood Institute (NHLBI), Office of the Director, National Institutes of Health (OD)
Conditions	Cardiovascular Diseases, Cardiac Rehabilitation
Enrollment	400 participants
Start Date	2026-04-01
Primary Completion	2030-06-30 (estimated)
Study Completion	2030-08 (estimated)
Updated on ClinicalTrials.gov	2026-04-28