Clinical Trial

CorVad Myocardial Infarction Complicated with Cardiogenic Shock Trial

Study acronym: Corvad AMICS
Not Yet Recruiting
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Summary
Cardiogenic shock a serious complication of a heart attack (myocardial infarction). Despite evaluation of several new treatments during the last decade, the mortality in patients with cardiogenic shock still exceeds 50%. An alternative to current management is restoration of the volume of blood pumped by the heart (cardiac output) using a ventricular assist device. In the acute setting this is difficult but can be done using the CorVad device which is a catheter-based, axial flow pump that pumps blood directly from the left ventricle into the circulation thereby restoring blood flow to the failing organs. The hypothesis of the current study is to reduce mortality and morbidity of patients with cardiogenic shock using the CorVad device. The study will be carried out as a randomized multicenter study where eligible patients will be randomized to receive conventional circulatory support or support with the CorVad device and inotropic support if needed. A total of 269 patients are planned
Trial Details
NCT Number NCT06886113
Lead Sponsor Shenzhen Core Medical Technology CO.,LTD.
Conditions Cardiogenic Shock
Enrollment 269 participants
Start Date 2025-10-01
Primary Completion 2026-08-31 (estimated)
Study Completion 2028-02-15 (estimated)
Updated on ClinicalTrials.gov 2025-03-20