ALS Research Collaborative

The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings will help with drug discovery, biomarker discovery, and outcome measure validation. Adults living with ALS, other motor neuron diseases (MND), a known mutation related to ALS and healthy volunteers contribute prospective and retrospective data to this study remotely. The study is sponsored and conducted by the ALS Therapy Development Institute.

NCT Number	NCT06885918
Lead Sponsor	ALS Therapy Development Institute
Conditions	Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), ALS With Frontotemporal Dementia (ALS/FTD), Motor Neuron Disease, Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Enrollment	2,000 participants
Start Date	2014-09-12
Primary Completion	2035-01-31 (estimated)
Study Completion	2035-01-31 (estimated)
Updated on ClinicalTrials.gov	2025-03-20