Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06884540 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: The OPUS Anesthesia Pilot Trial

Study acronym: OPUS
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Trial status changed: Recruiting → Active, Not Recruiting
    • Study sites: 3 to 5
    v6
  2. Study sites: 1 to 3
    • Eligibility criteria expanded, about 6 words
    v5
  3. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Jul 2025 to Jul 15, 2025
    • Site details revised
    v4
  4. Re-verified, no change to tracked fieldsv3
  5. Start date: Apr 2025 to Jul 2025v2
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Up to 40% of patients experience suboptimal recovery in the days following major surgery, limiting their return to functional independence. Few preventive interventions exist, but intravenous dexmedetomidine and lidocaine administered during general anesthesia represent simple strategies that may significantly impact recovery and other patient-centred outcomes after surgery. The goal of this pilot trial is to determine the feasibility of conducting a phase 3 pragmatic adaptive multicentre trial to evaluate the impact of dexmedetomidine and lidocaine administered during major non-cardiac surgery on patient-centred outcomes.
Trial Details
NCT Number NCT06884540
Lead Sponsor CHU de Quebec-Universite Laval
Collaborators: Canadian Perioperative Anesthesia Clinical Trials (PACT) Group, Canadian Institutes of Health Research (CIHR), International Anesthesia Research Society (IARS)
Conditions
(from sponsor)		 Anesthesia, Anesthesia Complication, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity, Feasibility Studies, Patient-centredness
Related terms Postoperative Pain
Enrollment 100 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov