Clinical Trial

Spinal Palliation in Irradiation for Neoplastic Analgesia and Life Quality

Study acronym: SPINAL
Recruiting
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Summary
The goal of this clinical trial is to assess the impact of reducing the volume of palliative metastatic bone irradiation on analgesic effectiveness at day 30 and to evaluate the efficiency of telemonitoring in identifying patients who could benefit from Patient-Reported Outcomes (PROs) and require care. These objectives will be addressed in a multicenter, randomized, prospective study with two arms: A standard arm with spinal irradiation without sparing the adjacent vertebrae. An experimental arm with spinal irradiation sparing the adjacent vertebrae. The results will determine whether reducing the irradiated volume can maintain effective pain relief while minimizing side effects.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-03-17; most recent amendment 2025-09-22.
Status change: Not Yet Recruiting → Recruiting 2025-07-08
Trial Details
NCT Number NCT06884332
Lead Sponsor Institut de Cancérologie de Lorraine
Conditions Bone Metastasis, Oncology Pain
Enrollment 598 participants
Start Date 2025-07-02
Primary Completion 2027-07-02 (estimated)
Study Completion 2029-01-02 (estimated)
Updated on ClinicalTrials.gov 2025-09-23