Clinical Trial

Application of Plant Protection Products (PPP) in Apple Orchards

Study acronym: aPPPle
Recruiting
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Record status
This record was last updated March 19, 2025 (before its estimated December 20, 2025 completion). Its status may not reflect the trial's current state.
Summary
The aim of the aPPPle pilot study is to test feasibility and generate first results in preparation for a main study. The aPPPle study will investigate the exposure of operators, workers and residents to plant protection products (PPP) and potential physiological effects on blood biomarkers. The target plants are apple crops, as application occurs at higher altitudes and therefore higher drift/exposure is expected compared to ground-level application. The substances to be investigated are acetamiprid (an insecticide) and dithianon and dodine (two fungicides).
Trial Details
NCT Number NCT06884189
Lead Sponsor German Federal Institute for Risk Assessment
Collaborators: Federal Ministry of Food and Agriculture, ESTEBURG Obstbauzentrum Jork Kompetenzzentrum für den norddeutschen Obstbau
Conditions Dermal Exposure, Inhalative Exposure, Metabolites in Urine, Effekt Biomarker in Blood
Enrollment 16 participants
Start Date 2025-03-11
Primary Completion 2025-12-20 (estimated)
Study Completion 2025-12-20 (estimated)
Updated on ClinicalTrials.gov 2025-03-19