Clinical Trial

Clinical Relevance of Pathologic Regression IN Lymph Node for Locally Advanced Rectal Cancer

Enrolling by Invitation
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Record status
This record was last updated March 19, 2025 (before its estimated December 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
We evaluated all related clinical and pathologic data of patients with Locally Advanced Rectal Cancer following Neoadjuvant Chemoradiotherapy, including the pathologic regression grading in the primary tumor site and lymph node, and other histopathologic characteristics. Finally, the present study was aimed at (1) clarifying the clinical significance of the Major Pathologic Regression for Locally Advanced Rectal Cancer following Locally Advanced Rectal Cancer in the primary tumor site and lymph node, and (2) comparing different Neoadjuvant Chemoradiotherapy treatments of this uncommon disease through conducting a large, multi-center cohort study.
Trial Details
NCT Number NCT06883084
Lead Sponsor Yanhong Deng
Conditions Rectal Cancer, Lymph Node Metastasis
Enrollment 1,080 participants
Start Date 2014-01-30
Primary Completion 2025-12-30 (estimated)
Study Completion 2026-02-25 (estimated)
Updated on ClinicalTrials.gov 2025-03-19