Biliary Dilatation National Special Disease Cohort in China

This study is a multicenter, bidirectional cohort study aimed at continuously enrolling patients with biliary dilatation from 25 medical centers in China. It will collect comprehensive life-cycle data from the cohort to establish a Chinese cohort for bile duct dilatation. Based on this cohort, the study seeks to clarify the epidemiological characteristics, pathological features, standard classification, disease progression, cancer risk, and optimal timing for surgical intervention in patients with bile duct dilatation. Additionally, it will compare the perioperative risks, long-term outcomes, and quality of life among different types of patients (including Todani types I, IVa, and V) following surgical treatment, to establish standardized surgical treatment strategies for each type.

NCT Number	NCT06881004
Lead Sponsor	Beijing Tsinghua Chang Gung Hospital
Conditions	Choledochal Cyst
Enrollment	6,000 participants
Start Date	2025-03-19
Primary Completion	2035-03-31 (estimated)
Study Completion	2035-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-23