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KPD Consolidation After ASCT in NDMM Patients

StatusRecruiting
PhasePhase 2/3
Started2025-03
View on ClinicalTrials.gov ↗
This study aims to evaluate the efficacy and safety of post-transplant consolidation therapy with the KPD regimen (carfilzomib, pomalidomide, and dexamethasone) versus no consolidation, followed by maintenance therapy, in patients with transplant-eligible newly diagnosed multiple myeloma (TE-NDMM). The primary goal is to compare minimal residual disease (MRD) negativity rates and overall treatment outcomes between the two groups.
Trial Details
NCT Number NCT06879379
Lead Sponsor Peking University People's Hospital
Conditions Multiple Myeloma, Newly Diagnosed
Enrollment 202 participants
Start Date 2025-03
Primary Completion 2028-03 (estimated)
Study Completion 2029-03 (estimated)
Updated on ClinicalTrials.gov 2025-03-17