Trauma and Cardiometabolic Health in an American Indian Community

Volunteers for the study are asked to participate in two laboratory sessions. In the first laboratory session, volunteers are asked to provide a blood sample which will be used to measure factors related to health. Participants also complete questionnaires related to demographic and health-related information and undergo evaluations of their body composition. In the second laboratory visit, participants are asked to have cardiovascular, neuroendocrine, and inflammatory activity measured during a brief period of rest and during a short challenging psychological task. Participants will also complete questionnaires. The study is designed to examine the associations between experiences such as trauma and resiliency with changes in bodily systems during a challenge and current health.

NCT Number	NCT06878885
Lead Sponsor	Montana State University Collaborators: National Heart, Lung, and Blood Institute (NHLBI), Baylor University, Blackfeet Community College
Conditions	Psychological Stress, Cardiometabolic Conditions, Mental Health
Enrollment	400 participants
Start Date	2024-05-10
Primary Completion	2027-06-30 (estimated)
Study Completion	2027-06-30 (estimated)
Updated on ClinicalTrials.gov	2025-03-17