Clinical Trial

Rapid Diagnostic Technology for AUGIB Based on Analysis of VOCs in Exhaled Breath

Study acronym: VOCsAUGIB
Not Yet Recruiting
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Record status
This record was last updated March 14, 2025 (before its estimated July 20, 2025 completion). Its status may not reflect the trial's current state.
Summary
This study aims to develop a non-invasive and rapid diagnostic technology for acute upper gastrointestinal bleeding (AUGIB) by analyzing volatile organic compounds (VOCs) in exhaled breath. Clinically confirmed patients will be divided into three groups (no bleeding, minor bleeding, major bleeding) based on endoscopic findings. VOC profiles will be analyzed to construct a predictive model, validated for sensitivity and specificity (both targets ≥0.7). This approach addresses the limitations of endoscopy in emergency or resource-limited settings, improving diagnostic efficiency and reducing mortality.
Trial Details
NCT Number NCT06877507
Lead Sponsor Beijing 302 Hospital
Conditions Volatile Organic Compound, Gastrointestinal Hemorrhage
Enrollment 200 participants
Start Date 2025-03-20
Primary Completion 2025-07-20 (estimated)
Study Completion 2025-07-20 (estimated)
Updated on ClinicalTrials.gov 2025-03-14