Clinical Trial

MR-Evaluation of Renal Function in Anesthetized Pediatric Patients

Study acronym: MERAPED
Not Yet Recruiting Phase 4
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Summary
The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys. Pediatric patients who are planned to undergo an MRI scan with generalized anesthesia will be randomized to either IV anesthesia with propofol or inhalation anesthesia with sevoflurane. Both of these anesthetic methods are commonly used for anesthesia on an everyday basis. In addition to the clinically indicated MRI, Multiparametric MRI will be performed to visualize the effect of the anesthetic agent on renal blood flow, perfusion and oxygenation.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-03-10.
Trial Details
NCT Number NCT06876870
Lead Sponsor Uppsala University
Collaborators: Uppsala University Hospital
Conditions Renal Blood Flow, Anesthesia, MRI, Renal Oxygenation
Enrollment 50 participants
Start Date 2025-10-01
Primary Completion 2026-12-10 (estimated)
Study Completion 2027-06-20 (estimated)
Updated on ClinicalTrials.gov 2025-03-25