Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction

This study aims to investigate the effects of motor-cognitive interactive robot-assisted training on improving upper limb motor dysfunction after stroke. By observing different combinations of motor and cognitive components in the training, the study will clarify the relationship between the proportion of motor and cognitive elements and the recovery of upper limb motor function. The goal is to optimize the training protocol for upper limb rehabilitation robots and enhance their therapeutic outcomes. Participants will be randomly assigned to one of three groups: motor-cognitive interactive robot-assisted training, motor-focused robot-assisted training, or conventional rehabilitation training. Training sessions will last 60 minutes, occur 5 times per week, and continue for 4 weeks. Researchers will measure changes in upper limb function and monitor for any adverse events during the training.

NCT Number	NCT06876597
Lead Sponsor	Lidian Chen Collaborators: Fujian University of Traditional Chinese Medicine Affiliated Rehabilitation Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, China Rehabilitation Research Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China, Shanghai Sunshine Rehabilitation Center
Conditions	Stroke
Enrollment	1,047 participants
Start Date	2025-04-08
Primary Completion	2026-12-31 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-04-24